Of all the places to go in this beautiful country, a weekend trip to San Diego could be at the top of the list. Located just 17 miles north of Mexico, San Diego boasts beautiful beaches, warm weather, and endless attractions. If you have time for a road trip, Palm Springs, Los Angeles, and Joshua Tree National Park are all within driving distance. The quaint town of Julian is about an hour drive away and known around the USA for its world-famous pies. But there is so much to on a weekend getaway in San Diego that you may never want to leave.

If you want to see a lot of attractions, consider purchasing a San Diego CityPass. The pass gets you steep discounts on attractions like Legoland, Sea World, and Old Town Trolley tours.

Quick Answer: Best Weekend Trips to San Diego

Most Popular Neighborhoods in San Diego

San Diego is a large city with many different areas. Each of the neighborhoods in San Diego have something unique to offer, from La Jolla's miles of coastline, to Gaslamp Quarter's bars and nightlife, to Coronado, which is actually its own island! Here are highlights of three of the most popular neighborhoods in San Diego.

1. La Jolla

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  • Perfect for:‌ Couples who love the ocean
  • Highlights of La Jolla:
    • Only 25 minutes from the airport
    • Close to beaches and restaurants
    • Moderate average hotel prices

Things to Do in La Jolla‌ If you're looking for a luxurious and romantic weekend getaway in San Diego, La Jolla is the perfect destination. This upscale seaside community boasts some of the most beautiful beaches in San Diego, including Windansea Beach.

La Jolla Cove is well known for its crystal clear blue waters and sea lions. While you're there, be sure to visit the charming boutiques and galleries on Prospect Street.

I highly recommend dining at The Cottage for a cozy breakfast and brunch setting, try their amazing huevos rancheros! For dinner make a reservation at George's at the Cove, an upscale restaurant that offers stunning views of the ocean and serves innovative California Baja cuisine made with fresh, local ingredients.

If you're looking for a unique outdoor experience, the Torrey Pines State Natural Reserve is an excellent choice. This reserve features several hiking trails that offer stunning views of the ocean and the surrounding landscapes. The reserve is also home to the rare Torrey pine tree, which can only be found in this specific region.

How to Get to La Jolla‌ La Jolla is located about 20 minutes north of San Diego International Airport. The most convenient way to get there is by taking a taxi, Lyft, or Uber. Alternatively, you can take the 30 bus from the airport to La Jolla Village Drive & Torrey Pines Road.

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Where to Stay in La Jolla‌ La Jolla has no shortage of gorgeous Airbnbs and luxurious hotels to suit every traveler's needs.

This Airbnb guest suite offers a backyard garden with breathtaking 180-degree ocean views and amazing sunsets; perfect for couples.

Ocean-view Airbnb in La Jolla Book Now

For a more luxurious experience, check out the Pantai Inn. This charming boutique hotel offers cozy accommodations with Balinese-inspired decor. The hotel features a courtyard with a koi pond, a rooftop terrace, a library, and beach access.

Pantai Inn La Jolla Book Now

2. Gaslamp Quarter

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  • Perfect for:‌ Foodies and nightlife
  • Highlights of the Gaslamp Quarter:
    • Only 10 minutes from the airport
    • Moderate average hotel prices
    • Walking distance to many restaurants

Things to Do In Gaslamp Quarter‌ The Gaslamp Quarter is the place to be for a more lively San Diego weekend trip. This neighborhood is home to some of the best bars, nightclubs, and restaurants in San Diego, making it perfect for those looking for a night out on the town.

During the day, you can explore the area's rich history by visiting the Gaslamp Museum or taking a walking tour of the neighborhood's beautiful Victorian buildings.

If you're in the mood for Spanish cuisine, head to Cafe Sevilla. This lively restaurant offers tapas, paella, and live Flamenco shows, making it a great spot for a night out with friends or a romantic evening with your significant other.

After dinner head on down to The Tipsy Crow, a historic bar located in the heart of the Gaslamp Quarter. The Tipsy Crow offers a lively atmosphere with multiple levels, a dance floor, and a variety of craft cocktails and local beers. This spot is perfect for those looking to dance the night away.

How to Get to Gaslamp Quarter‌ The Gaslamp Quarter is located about 15 minutes southeast of San Diego International Airport. The most convenient way to get there is by taking a taxi, Lyft, or Uber. Alternatively, you can take the Green Line Trolley to the Gaslamp Quarter Station.

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Where to Stay in Gaslamp Quarter‌ Consider booking a room at the Hard Rock Hotel San Diego. This stylish hotel has a rock-and-roll theme throughout, with music-inspired decor and a rooftop pool and lounge area.

Hard Rock Hotel San Diego Book Now

For a more private getaway, this condo-style Airbnb offers a garden patio and a modern kitchen with a built-in wine fridge.

Condo-style Airbnb Book Now

3. Coronado

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  • Perfect for:‌ Beach and watersports
  • Highlights of Coronado:
    • Only 15 minutes from the airport
    • Plenty of outdoor activities
    • High-end hotels

Things to Do in Coronado‌ A weekend trip to San Diego can't be complete without a stop in Coronado. Coronado is actually its own island, located just across the bay from downtown San Diego. This picturesque community is known for some of San Diego’s best beaches, luxurious resorts, and a charming downtown area.

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While you're there, be sure to check out the Hotel del Coronado. This historic hotel, which dates back to 1888, is an icon of the island and a must-see attraction. Take a stroll through the lobby and grounds to admire the Victorian architecture, then grab a drink or a bite to eat at one of the hotel's restaurants or bars.

From the hotel, it’s just a short walk down to the world-famous Coronado Beach with its wide expanse of sand and sparkling blue water.

Rent a bike and explore the island on two wheels. With its flat terrain and scenic paths, Coronado is the perfect place for a leisurely bike ride. Stop by the Wheel Fun Rentals bicycle rental shop for rentals and maps.

End your perfect day with some fine dining at Serẽa, an upscale restaurant at the Hotel del Coronado with a focus on fresh seafood and locally sourced ingredients. The menu changes seasonally and features creative and delicious dishes, such as tuna tartare, oyster platters, and risotto with truffles.

How to Get to Coronado‌ Coronado is located about 20 minutes south of San Diego International Airport. The easiest way to get there is by taking a taxi, Lyft, or Uber to the Coronado Bridge. You can also take the 901 bus from the airport to Broadway & 2nd, and then transfer to the 901 bus to Coronado.

Where to Stay in Coronado‌ Apart from the stunning Hotel del Coronado, there are a variety of resorts, boutique hotels, and Airbnbs available throughout the island.

You can’t go wrong with the Coronado Beach Resort, a boutique hotel located in the heart of Coronado's charming downtown area that offers spacious suites with full kitchens, living rooms, and private balconies. The hotel also features a rooftop deck with stunning views of the ocean and the island.

Coronado Beach Resort Book Now

For a more intimate experience, this exquisitely designed beach studio is just a 5-minute walk away from the shore.

Beach studio Airbnb Book Now

Cool & Unique Areas of San Diego

Of all of the cities in California, there are truly some cool and unique areas that you can only find in San Diego. Yes, there are a lot of beaches! But each one has its own vibe and style, so check them all out, from Pacific Beach to North Park to Little Italy.

4. Pacific Beach

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  • Perfect for:‌ Surfers and beach lovers
  • Highlights of Pacific Beach:
    • Only 15 minutes from the airport
    • Moderate average hotel prices
    • Good balance of outdoor activities, nightlife, and restaurants

Things to Do in Pacific Beach‌ It can be hard to decide what to do in San Diego for a weekend, but if you're looking for a laid-back beach town vibe, Pacific Beach is the perfect destination. This neighborhood is home to a bustling boardwalk, plenty of surf shops, and some of the best bars and restaurants in San Diego. Day trips to La Jolla or nearby Ocean Beach are a breeze from this central location.

During the day, you can catch some waves or soak up the sun on Tourmaline Beach and then grab an afternoon cocktail at Lahaina’s Beach Bar (cash only!).

For lunch, you can experience some of the best tacos that southern California has to offer at Oscars, Taco Surf, or City Tacos; take your pick.

Be sure to return to the beach in time for a breathtaking sunset at Law Street Park, and then head over to Garnet Ave for endless dinner and nightlife options.

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How to Get to Pacific Beach‌ Pacific Beach is located about 20 minutes northwest of San Diego International Airport. The easiest way to get there is by taking a taxi, Lyft, or Uber. Alternatively, you can take the 992 bus from the airport to Pacific Beach Drive & Mission Boulevard.

Where to Stay in Pacific Beach‌ Pacific Beach, or “PB” as the locals call it, is chock full of beachfront hotels and cozy Airbnb options.

This beach cottage boasts a private backyard complete with a fire pit, all just minutes away from lovely Mission Bay.

Pacific Beach cottage Airbnb Book Now

If you want to be closer to the beach, Tower 23 Hotel offers stunning ocean views from its rooms and suites. The hotel features a rooftop lounge, a restaurant, and a spa, as well as easy access to the boardwalk and beach.

Tower 23 Hotel Book Now

5. North Park

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  • Perfect for:‌ Beer enthusiasts and art lovers
  • Highlights of North Park:
    • Close proximity to downtown and other attractions
    • Below-average hotel prices
    • Right on the public bus line

Things to Do in North Park‌ If you're spending 3 nights in San Diego be sure to stop by North Park; a hip and happening neighborhood that is popular with young professionals and creatives. The area is home to numerous art galleries, vintage shops, and craft breweries.

Beer enthusiasts can enjoy world-renowned brews at North Park Brewing, Pure Tasting Room, and Original 40.

One of the standout destinations in North Park is the Observatory North Park, a music venue that has hosted acts such as Arcade Fire, Lorde, and the Black Keys. If you're a music lover, be sure to check their calendar for upcoming shows.

For a unique dining experience, head over to Sipz Vegetarian Kitchen. This plant-based eatery offers a fusion of Asian, Mexican, and American flavors, with dishes like veggie pho, vegan tacos, and tempeh burgers.

How to Get to North Park‌ North Park is located about 15 minutes northeast of San Diego International Airport. The most convenient way to get there is by taking a taxi, Lyft, or Uber. Alternatively, you can take the 992 bus from the airport to El Cajon Boulevard & Texas Street.

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Where to Stay in North Park‌ The flagship hotel in North Park is The Lafayette. This historic hotel dates back to the 1940s and has been lovingly restored to its former glory. The hotel boasts a heated pool, poolside bar, and live music events.

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There are also dozens of cozy Airbnb options, including this bungalow oasis complete with designated parking and a private outdoor area.

Bungalow oasis Airbnb Book Now

6. Little Italy

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  • Perfect for:‌ Romantic getaways and foodies
  • Highlights of Little Italy:
    • Only 10 minutes from the airport
    • An abundance of restaurants and nightlife options
    • Walking distance to many attractions
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Things to Do in Little Italy‌ Little Italy is a must-see for any San Diego weekend trip. This charming area of town is packed with restaurants, cafes, and gelato shops that will make you feel like you've been transported to Italy itself.

The main street, India Street, is lined with colorful umbrellas and outdoor seating, making it the perfect spot to enjoy some Italian al fresco dining. Be sure to stop by Piazza della Famiglia, a public square that hosts weekly farmers markets and live music events.

If you're a fan of craft beer, head over to Ballast Point Brewery to try some of their award-winning brews. The brewery is housed in a former homebrew supply store and has a spacious outdoor patio where you can enjoy a pint with a view of the harbor.

How to Get to Little Italy‌ Little Italy is located about 10 minutes northwest of San Diego International Airport. The easiest way to get there is by taking a taxi, Lyft, or Uber. Alternatively, you can take the 992 bus from the airport to India and West Ash Street.

Where to Stay in Little Italy‌ Consider booking a room at the La Pensione Hotel. This boutique hotel is located right in the heart of Little Italy and offers stylish rooms with European flair. The hotel also has a rooftop terrace where you can take in views of the city skyline.

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Located right in the heart of Little Italy, this Airbnb offers unmatched privacy and convenience.

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Hidden Gems of San Diego

When it comes to San Diego, there are plenty of hidden gems to discover beyond the well-known tourist spots. These are places that don't often come up when people are planning on what to do in San Diego for a weekend. Here are a few off-the-beaten-path destinations that are worth checking out on your weekend trip.

7. Hillcrest

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  • Perfect for:‌ Foodies and fans of nightlife
  • Highlights of Hillcrest‌:
    • Only 15 minutes from the airport
    • Located on the public bus line
    • Walking distance to bars, clubs, and restaurants
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Things to Do in Hillcrest‌ Hillcrest is known for its trendy restaurants, cafes, and boutique shops. If you're a foodie, you'll love the diverse range of dining options here. Some of my favorites include Snooze, a breakfast joint famous for its pancake flights, and Hash House a Go Go, which serves oversized portions of delicious comfort food.

Nearby Balboa Park offers a plethora of museums, historical sites, and the world-famous San Diego Zoo.

If you're into vintage shopping, check out Flashbacks Recycled Fashion or Hunt & Gather. For a fun night out, head to Gossip Grill, a popular bar with excellent cocktails and live music.

How to Get to Hillcrest‌ Hillcrest is located about 15 minutes north of San Diego International Airport. The most convenient way to get there is by taking a taxi, Lyft, or Uber. Alternatively, you can take the Green Line Trolley to the Hillcrest Station.

Where to Stay in Hillcrest
If you're looking for a unique and stylish place to stay in Hillcrest, I recommend checking out the Inn at the Park. This historic hotel features Spanish-style architecture, a rooftop terrace with stunning views, and comfortable guest rooms.

Inn at the Park Book Now

For a more intimate setting, consider this charming craftsman bungalow just one block away from many restaurants, bars, and nightclubs.

Charming Hillcrest craftsman bungalow Book Now

8. Old Town

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  • Perfect for:‌ History buffs and traditional Mexican cuisine
  • Highlights of Old Town:
    • Only 10 minutes from the airport
    • Located on the public bus line
    • A rich blend of museums, historical sites, and restaurants

Things to Do in Old Town‌ If you have a chance during your 3 nights in San Diego, Old Town is a historic neighborhood that's known for its preserved architecture, museums, and Mexican cuisine. Some of the top attractions here include the Whaley House Museum, the Old Town San Diego State Park, and the Bazaar del Mundo shops.

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For dining, make sure to try some of the fantastic Mexican food options, such as Casa de Reyes, Old Town Mexican Cafe, or Café Coyote.

How to Get to Old Town‌ Old Town is located about 10 minutes north of San Diego International Airport. The easiest way to get there is by taking a taxi, Lyft, or Uber. You can also take the Green Line Trolley to the Old Town Transit Center.

Where to Stay in Old Town‌ For a unique and authentic experience, I recommend staying at the Cosmopolitan Hotel and Restaurant, which is located within the Old Town San Diego State Historic Park. This historic hotel features 10 guest rooms, a restaurant with live music, and beautiful courtyard gardens.

Cosmopolitan Hotel and Restaurant Book Now

There are some lovely authentic Mexican-style Airbnb options located in Old Town as well. I highly suggest Casita Atras de Felicidad, a beautiful single-bedroom home complete with a private outdoor patio area.

Casita Atras de Felicidad Book Now

9. Ocean Beach

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  • Perfect for:‌ Laid back vibes, beaches, and fishing
  • Highlights of Ocean Beach:
    • Only 15 minutes from the airport
    • Moderate average hotel prices
    • Located on the public bus line
    • Something for everyone

Things to Do in Ocean Beach‌ Ocean Beach is a laid-back, bohemian neighborhood known for its beautiful beaches, surf culture, and eclectic shops. Spend a day at the beach or explore the unique shops, such as Ocean Beach Antique Mall or OB Surf & Skate.

Visit one of the many nearby watersports rental stores and do some fishing off the OB Pier or kayaking in Mission Bay.

For dining, check out Hodad's, a local favorite burger joint, or South Beach Bar & Grille, which serves delicious seafood and margaritas.

How to Get to Ocean Beach‌ Ocean Beach is located about 15 minutes west of San Diego International Airport. The most convenient way to get there is by taking a taxi, Lyft, or Uber. You can also take the 923 bus from the airport to Newport Avenue, the main street in Ocean Beach.

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Where to Stay in Ocean Beach‌ For a comfortable and affordable stay in Ocean Beach, I recommend checking out the Ocean Villa Inn. This beachfront hotel features cozy guest rooms, a heated pool, and complimentary beach chairs and towels.

Ocean Villa Inn Book Now

If you are looking for a more cozy and intimate setting, this dog-friendly Airbnb beach cottage is less than two blocks from the shore and five blocks from an assortment of restaurants and bars.

Dog-friendly Ocean Beach Airbnb Book Now

10. Point Loma

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  • Perfect for:‌ Romantic sunsets and fine dining
  • Highlights of Point Loma:
    • Only 10 minutes from the airport
    • A great mix of outdoor activities, shopping, and dining
    • Located on the public bus line

Things to Do in Point Loma‌ Point Loma is a beautiful and affluent neighborhood known for its stunning ocean views, historic landmarks, and upscale dining options.

Visit the Cabrillo National Monument, a park with hiking trails, tide pools, and a lighthouse. Check out the Point Loma Seafood Market & Restaurant, which serves fresh seafood with ocean views.

End your day with a quick trip to Sunset Cliffs and experience a world-renowned Southern California Sunset; this is a must-visit.

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How to Get to Point Loma‌ Point Loma is located about 10 minutes northwest of San Diego International Airport. The easiest way to get there is by taking a taxi, Lyft, or Uber. You can also take the 28 bus from the airport to Point Loma Avenue & Rosecrans Street.

Where to Stay in Point Loma‌ For a luxurious and tranquil stay in Point Loma, I recommend checking out the Kona Kai Resort & Spa. This waterfront resort features elegant guest rooms, a private beach, multiple swimming pools, and a full-service spa.

Kona Kai Resort & Spa Book Now

This lovely guest suite offers a more private experience with two bedrooms and a private deck for dining, grilling, or lounging.

Lovely Airbnb guest suite Book Now

San Diego is one of the most vibrant cities in the country, so I hope that this 3-night getaway guide has given you some ideas for how you could spend some time on your weekend trip to San Diego.